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While metoprolol can contribute to erectile dysfunction in some men, not everyone will experience this side effect. If you believe the medication is affecting your sexual health, it’s important to talk to your doctor. They can help determine the cause and discuss alternatives or strategies to manage the issue. Beta-blockers, including metoprolol, work by lowering heart rate and reducing blood pressure, which in turn can affect blood flow throughout the body, including to the penis. Erectile function relies heavily on adequate blood flow, so any medication that alters circulation can potentially lead to difficulties in achieving or maintaining an erection. Yes, Metoprolol and ED, which is a beta-blocker commonly prescribed for high blood pressure, heart disease, and other cardiovascular conditions, can contribute to erectile dysfunction (ED) in some individuals. While not everyone who takes metoprolol will experience ED, it is a potential side effect for some men.